WEBVTT
Kind: captions
Language: en

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Hello, everyone. I'm Pei-Shan Tsai, a
professor of Nursing from Taipei Medical University.

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For today's lecture, I'm going
to talk about Mind-Body connection.

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This is the outline that today's talk.

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I will first introduce the relationship between stress and health.

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Mechanisms underlying Mind-Body connection will be discussed.

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Next, I will talk about Stress-related
illness, mind-body interventions.

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Finally, I will present findings from a recent Meta-Analysis to give you some ideas

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on the effects of Mind-body interventions on sleep in cancer patients.

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Stress is defined as "any stimulus, such as fear or pain, that disturb or interferes with the

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normal physiologic homeostasis of an organism."

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Chronic stress causes wear and tear on your body.

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Stress is an important determinant of a person's health

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The reason why stress causes illness remains illusive.

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However, potential mechanisms have been proposed to explain the link between mind and body.

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It is become increasingly evident that there exists bi-directional interactions

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between the brain and the peripheral tissues.

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Specific fronto-temporal cortical regions in the representation and control of adverse symptoms,

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which interact reciprocally with subcortical structures

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involved in bodily homeostasis and responses to stress.

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Bidirectional autonomic and neuroendocrine pathways transmit information

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between the central nervous system and the periphery

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and facilitate the expression of affective, 
autonomic, hormonal, and immune responses.

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A recent elegantly performed study by
neuroscientists at the University of Pittsburgh

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uncovered evidence for the neural basis of a mind-body connection.

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They have identified the neural networks
that connect the cerebral cortex to the adrenal medulla,

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which is responsible for the body's rapid response in stressful situations.

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In their experiments, the scientists traced the neural circuitry that links areas of the cerebral cortex

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to the adrenal medulla, which is the inner part of the adrenal gland located above each kidney.

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According to their findings, the biggest influences arise from motor areas of the cerebral cortex

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and from other cortical regions 
involved in cognition and emotion.

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These results indicate that circuits exist to link movement, cognition, emotion

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to the function of the adrenal medulla and the control of stress.

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This circuitry may mediate the effects of chronic stress and depression on organ function.

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This is the reference.

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Stress-related conditions include: anxiety, coronary heart disease, depression,

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fatigue, fibromyalgia, hypertension, insomnia, irritable bowel syndrome,

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and posttraumatic stress disorder.

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These are just some examples.

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Mind-body interventions focus on the relationships among the brain, mind, body and behavior,

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and their effect on health and disease.

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Mind-body interventions encompass 
a large group of therapies.

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such as relaxation and breathing, tai chi, qi gong, yoga, meditation and biofeedback.

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Many of the mind-body interventions are thought to be beneficial for conditions

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where psychological stress is a factor.

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Now, I would like to share with you findings from a recent Meta-Analysis.

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This study was done by my research team

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We evaluated the effects of Mind-body interventions on sleep in cancer patients.

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This Meta-Analysis included 15 randomized controlled trials.

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A total of 16 effect sizes were calculated.

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Mind-body intervention, evaluate in this study, including yoga, mindfulness-based stress reduction,

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mind-body bridging, meditation, hypnosis and qigong

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Mind-body interventions exerted a median effect size for sleep improvement in cancer patients.

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And these effects lasted up to three months.

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Here are some clinical points 
that we learn from this study.

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Sleep disturbance is a pervasive symptom in cancer patients that impairs quality of life.

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A Meta-Analysis of mind-body interventions 
among cancer patients

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yielded moderate improvement in sleep quality that persisted up to three months.

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Mind-body interventions should be considered as adjunctive or complementary therapies

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in the management of sleep problems experienced by cancer patients.

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Future studies should continue to explore nonpharmacological and lifestyles interventions

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for symptom improvement in cancer patients.

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Thank you for your attention.

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Until next time,  bye-bye