WEBVTT
Kind: captions
Language: en
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Comparison in the patient population.
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In terms of body weight again.
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Cockroft equation tend to overestimate.
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In the overweight patient, the overestimate is about 15 percent.
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In diabetes patient, the overestimate is 18 percent.
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And the diabetic obesity, the overestimate could be as high as 55 percent.
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Another method by Jelliffe, it is the Jelliffe method.
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For male is the top formula.
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Creatinine clearance is equal to 98 minus point 8
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times age minus 20 divided by serum creatinine.
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And for female,
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the formula says creatinine clearance is equal to 88 minus 0.7
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times age minus 20 divided by serum creatinine.
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Or simply, for the female the value
is 90 percent of male.
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This method was published by the investigator at UCLA Medical Center.
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Another formula Salazar and Corcoran equation for men and for women.
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For men the top formula and for women the bottom formula.
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And both formula involves age, weight, height and the serum creatinine.
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And the formula were derived from overweight population.
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Therefore, it provides better estimate for obese population.
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And the formulas were published by investigators at SUNY Buffalo Medical Center.
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And interestingly, based on these two formula.
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For men, the maximum life expectancy is 137.
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And for obese women, the maximum life expectancy is 146.
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Which is not bad at all.
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And this is compared also very closely with a hundred forty as suggested by the Cockcroft equation.
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Schwartz formula is for pediatric patient.
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It says creatinine clearance is equal to
K times height divided by serum creatinine.
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Now here K is a correction factor or adjustment factor.
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For example, point three three in Preemie infants.
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And the point five five in adolescent female.
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Please pay attention to the unit.
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Because this kind of formula is the so called empirical formula.
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You have to apply certain unit for the parameters in the formula.
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For example, in the Schwartz formula
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the height must be in centimeter,
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serum creatinine must be in milligram per decilitre.
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And the creatinine clearance is in the unit of milliliter per minutes.
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Now this formula was published by the investigator at University of Rochester Medical Center.